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rtM204Q May Serve as a Novel Lamivudine-Resistance-Associated Mutation of Hepatitis B Virus

BACKGROUND AND AIMS: Lamivudine (LAM) is still widely used for anti-HBV therapy in China. The study aimed to clarify whether a newly-found rtM204Q mutation from patients was associated with the drug resistance. METHODS: HBV complete reverse-transcriptase region was screened by direct sequencing and...

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Detalhes bibliográficos
Main Authors: Liu, Yan, Xu, Zhihui, Wang, Yan, Li, Xiaodong, Liu, Liming, Chen, Li, Xin, Shaojie, Xu, Dongping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933355/
https://ncbi.nlm.nih.gov/pubmed/24586482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089015
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