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Multiple genetic pathways regulate replicative senescence in telomerase-deficient yeast
Most human tissues express low levels of telomerase and undergo telomere shortening and eventual senescence; the resulting limitation on tissue renewal can lead to a wide range of age-dependent pathophysiologies. Increasing evidence indicates that the decline in cell division capacity in cells that...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3933227/ https://ncbi.nlm.nih.gov/pubmed/23672410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12099 |
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