Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants

BACKGROUND: The majority of coeliac disease (CD) patients are not being properly diagnosed and therefore remain untreated, leading to a greater risk of developing CD-associated complications. The major genetic risk heterodimer, HLA-DQ2 and DQ8, is already used clinically to help exclude disease. How...

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Detalhes bibliográficos
Main Authors: Romanos, Jihane, Rosén, Anna, Kumar, Vinod, Trynka, Gosia, Franke, Lude, Szperl, Agata, Gutierrez-Achury, Javier, van Diemen, Cleo C, Kanninga, Roan, Jankipersadsing, Soesma A, Steck, Andrea, Eisenbarth, Georges, van Heel, David A, Cukrowska, Bozena, Bruno, Valentina, Mazzilli, Maria Cristina, Núñez, Concepcion, Bilbao, Jose Ramon, Mearin, M Luisa, Barisani, Donatella, Rewers, Marian, Norris, Jill M, Ivarsson, Anneli, Boezen, H Marieke, Liu, Edwin, Wijmenga, Cisca
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Coeliac Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933173/
https://ncbi.nlm.nih.gov/pubmed/23704318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2012-304110
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