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Yeast genetic screen reveals novel therapeutic strategy for ALS
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by a selective loss of motor neurons. There is no cure and few effective treatments. The RNA-binding protein TDP-43 contributes to the pathogenesis of ALS. TDP-43 is depleted from the nucleus and accumulates in cytoplasmic agg...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3933050/ https://ncbi.nlm.nih.gov/pubmed/25002991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rdis.24420 |
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