Vaccination of monoglycosylated hemagglutinin induces cross-strain protection against influenza virus infections

The 2009 H1N1 pandemic and recent human cases of H5N1, H7N9, and H6N1 in Asia highlight the need for a universal influenza vaccine that can provide cross-strain or even cross-subtype protection. Here, we show that recombinant monoglycosylated hemagglutinin (HA(mg)) with an intact protein structure f...

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Autores principales: Chen, Juine-Ruey, Yu, Yueh-Hsiang, Tseng, Yung-Chieh, Chiang, Wan-Ling, Chiang, Ming-Feng, Ko, Yi-An, Chiu, Yi-Kai, Ma, Hsiu-Hua, Wu, Chung-Yi, Jan, Jia-Tsrong, Lin, Kuo-I, Ma, Che, Wong, Chi-Huey
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2014
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932897/
https://ncbi.nlm.nih.gov/pubmed/24469815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323954111
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