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ATP turnover by individual myosin molecules hints at two conformers of the myosin active site

Coupling of ATP hydrolysis to structural changes in the motor domain is fundamental to the driving of motile functions by myosins. Current understanding of this chemomechanical coupling is primarily based on ensemble average measurements in solution and muscle fibers. Although important, the averagi...

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Bibliografiske detaljer
Main Authors: Amrute-Nayak, Mamta, Lambeck, Katharina-Antonia, Radocaj, Ante, Huhnt, Helen Elisabeth, Scholz, Tim, Hahn, Nils, Tsiavaliaris, Georgios, Walter, Wilhelm J., Brenner, Bernhard
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932867/
https://ncbi.nlm.nih.gov/pubmed/24550279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316390111
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