Single-molecule analysis reveals that regulatory light chains fine-tune skeletal myosin II function

Myosin II is the main force-generating motor during muscle contraction. Myosin II exists as different isoforms that are involved in diverse physiological functions. One outstanding question is whether the myosin heavy chain (MHC) isoforms alone account for these distinct physiological properties. Un...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Nayak, Arnab, Wang, Tianbang, Franz, Peter, Steffen, Walter, Chizhov, Igor, Tsiavaliaris, Georgios, Amrute-Nayak, Mamta
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2020
Sujets:
Molecular Biophysics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242715/
https://ncbi.nlm.nih.gov/pubmed/32273340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012774
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