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Insights into mRNA export-linked molecular mechanisms of human disease through a Gle1 structure-function analysis
A critical step during gene expression is the directional export of nuclear messenger (m)RNA through nuclear pore complexes (NPCs) to the cytoplasm. During export, Gle1 in conjunction with inositol hexakisphosphate (IP(6)) spatially regulates the activity of the DEAD-box protein Dbp5 at the NPC cyto...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3932673/ https://ncbi.nlm.nih.gov/pubmed/24275432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2013.10.002 |
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