Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolites

An industrial microorganism Streptomyces avermitilis, which is a producer of anthelmintic macrocyclic lactones, avermectins, has been constructed as a versatile model host for heterologous expression of genes encoding secondary metabolite biosynthesis. Twenty of the entire biosynthetic gene clusters...

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Main Authors: KOMATSU, MAMORU, KOMATSU, KYOKO, KOIWAI, HANAE, YAMADA, YUUKI, KOZONE, IKUKO, IZUMIKAWA, MIHO, HASHIMOTO, JUNKO, TAKAGI, MOTOKI, OMURA, SATOSHI, SHIN-YA, KAZUO, CANE, DAVID E., IKEDA, HARUO
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932656/
https://ncbi.nlm.nih.gov/pubmed/23654282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/sb3001003
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