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Inhibition of erythrocyte sickling in vitro by DL-glyceraldehyde.

Concentrations of DL-glyceraldehyde between 5 and 20 mM reduce the sickling of S/S erythrocytes even in the complete absence of oxygen; at 10 mM glyceraldehyde the increase in the number of normal cells ranges from 20 to 40%. The inhibition of sickling was both concentration- and time-dependent and...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Nigen, A M, Manning, J M
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1977
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393262/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/264689/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.1.367
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