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Structural Basis of the Iron Storage Function of Frataxin from Single-Particle Reconstruction of the Iron-Loaded Oligomer()

The mitochondrial protein frataxin plays a central role in mitochondrial iron homeostasis, and frataxin deficiency is responsible for Friedreich ataxia, a neurodegenerative and cardiac disease that affects 1 in 40000 children. Here we present a single-particle reconstruction from cryoelectron micros...

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Bibliografski detalji
Glavni autori: Schagerlöf, Ulrika, Elmlund, Hans, Gakh, Oleksandr, Nordlund, Gustav, Hebert, Hans, Lindahl, Martin, Isaya, Grazia, Al-Karadaghi, Salam
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932613/
https://ncbi.nlm.nih.gov/pubmed/18393441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800052m
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