The Molecular Basis of Iron-induced Oligomerization of Frataxin and the Role of the Ferroxidation Reaction in Oligomerization

The role of the mitochondrial protein frataxin in iron storage and detoxification, iron delivery to iron-sulfur cluster biosynthesis, heme biosynthesis, and aconitase repair has been extensively studied during the last decade. However, still no general consensus exists on the details of the mechanis...

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Bibliographic Details
Main Authors: Söderberg, Christopher A. G., Rajan, Sreekanth, Shkumatov, Alexander V., Gakh, Oleksandr, Schaefer, Susanne, Ahlgren, Eva-Christina, Svergun, Dmitri I., Isaya, Grazia, Al-Karadaghi, Salam
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605634/
https://ncbi.nlm.nih.gov/pubmed/23344952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.442285
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