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Asymmetric Alcohol C-H Allylation and syn-Crotylation: C9-C20 of Tetrafibricin

[Image: see text] The C9-C20 segment of the fibrinogen receptor inhibitor tetrafibricin was prepared in 10 steps (longest linear sequence). Ruthenium catalyzed enantioselective syn-crotylation is used to construct C9-C13. Iridium catalyzed asymmetric alcohol C-H allylation of a commercial malic acid...

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Detalhes bibliográficos
Main Authors: Itoh, Takahiko, Montgomery, T. Patrick, Recio, Antonio, Krische, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932543/
https://ncbi.nlm.nih.gov/pubmed/24422777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol403566w
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