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βCaMKII in Lateral Habenula Mediates Core Symptoms of Depression

The lateral habenula (LHb) has recently emerged as a key brain region in the pathophysiology of depression. However the molecular mechanism by which LHb becomes hyperactive in depression remains unknown. Through a quantitative proteomic screen, we found that βCaMII expression was significantly upreg...

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Detalhes bibliográficos
Main Authors: Li, Kun, Zhou, Tao, Liao, Lujian, Yang, Zhongfei, Wong, Catherine, Henn, Fritz, Malinow, Roberto, Yates, John R., Hu, Hailan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932364/
https://ncbi.nlm.nih.gov/pubmed/23990563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1240729
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