Simple, sensitive and rapid determination of linifanib (ABT-869), a novel tyrosine kinase inhibitor in rat plasma by UHPLC-MS/MS

BACKGROUND: Linifanib (ABT-869) is an orally active receptor tyrosine kinase inhibitor, which simultaneously inhibits vascular endothelial and platelet derived growth factor receptor. The aim of the present study was to develop an UHPLC-MS/MS method for the quantification of linifanib in rat plasma...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Iqbal, Muzaffar, Ezzeldin, Essam, Wani, Tanveer A, Khalil, Nasr Y
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932137/
https://ncbi.nlm.nih.gov/pubmed/24533632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-153X-8-13
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki