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Islet antigen-specific Th17 cells can induce TNFα-dependent autoimmune diabetes
Type 1 diabetes (T1D) results from autoimmune destruction of pancreatic β-cells. Although Th1 cells are key orchestrators of T1D, the function(s) of the more recently identified Th17 subset are unclear due to inherent plasticity. Herein we analyzed Th17 cells for stability and diabetogenicity in NOD...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3932136/ https://ncbi.nlm.nih.gov/pubmed/24446517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301742 |
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