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The Antidepressant Trans-2-Phenylcyclopropylamine Protects Mice from High-Fat-Diet-Induced Obesity

Mice treated with the antidepressant trans-2-phenylcyclopropylamine (2-PCPA) were protected against diet-induced-obesity, and adiposity was reversed in pre-established diet-induced obese mice. Contrary to a recent report that inhibition of lysine-specific demethylase-1 by 2-PCPA results in increased...

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Bibliografiske detaljer
Main Authors: Shemesh, Adi, Abdulla, Arian, Yang, Fajun, Chua, Streamson C., Pessin, Jeffrey E., Zong, Haihong
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931726/
https://ncbi.nlm.nih.gov/pubmed/24586592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089199
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