Aryl Hydrocarbon Receptor Downregulates MYCN Expression and Promotes Cell Differentiation of Neuroblastoma

Neuroblastoma (NB) is the most common malignant disease of infancy. MYCN amplification is a prognostic factor for NB and is a sign of highly malignant disease and poor patient prognosis. In this study, we aimed to investigate novel MYCN-related genes and assess how they affect NB cell behavior. The...

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Bibliografiske detaljer
Main Authors: Wu, Pei-Yi, Liao, Yung-Feng, Juan, Hsueh-Fen, Huang, Hsuan-Cheng, Wang, Bo-Jeng, Lu, Yen-Lin, Yu, I-Shing, Shih, Yu-Yin, Jeng, Yung-Ming, Hsu, Wen-Ming, Lee, Hsinyu
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931655/
https://ncbi.nlm.nih.gov/pubmed/24586395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088795
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