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Molecular mechanism of action of immune-modulatory drugs thalidomide, lenalidomide and pomalidomide in multiple myeloma

Although several mechanisms have been proposed to explain the activity of thalidomide, lenalidomide and pomalidomide in multiple myeloma (MM), including demonstrable anti-angiogenic, anti-proliferative and immunomodulatory effects, the precise cellular targets and molecular mechanisms have only rece...

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Detalhes bibliográficos
Main Authors: Zhu, Yuan Xiao, Kortuem, K. Martin, Stewart, A. Keith
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931443/
https://ncbi.nlm.nih.gov/pubmed/22966948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2012.728597
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