Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple Negative Breast Tumor Therapeutic Target

A handful of tumor-derived cell lines form the mainstay of cancer therapeutic development, yielding drugs with impact typically measured as months to disease progression. To develop more effective breast cancer therapeutics and more readily understand their clinical impact, we constructed a function...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Timmerman, Luika A., Holton, Thomas, Yuneva, Mariia, Louie, Raymond J., Padró, Mercè, Daemen, Anneleen, Hu, Min, Chan, Denise A., Ethier, Stephen P., van ‘t Veer, Laura J., Polyak, Kornelia, McCormick, Frank, Gray, Joe W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931310/
https://ncbi.nlm.nih.gov/pubmed/24094812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2013.08.020
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