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Transcriptional Regulation of IFN-λ Genes in Hepatitis C Virus-infected Hepatocytes via IRF-3·IRF-7·NF-κB Complex

Hepatitis C virus (HCV) infection in hepatocytes stimulates innate antiviral responses including the production of type III interferons (IFN-λ), including IL-28A, IL-28B, and IL-29. However, the molecular mechanism(s) regulating the expression of IFN-λ genes in HCV-infected hepatocytes remains undef...

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Detalhes bibliográficos
Main Authors: Lee, Hai-Chon, Narayanan, Sowmya, Park, Sung-Jae, Seong, Seung-Yong, Hahn, Young S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931086/
https://ncbi.nlm.nih.gov/pubmed/24385435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536102
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