The TRPM6 Kinase Domain Determines the Mg·ATP Sensitivity of TRPM7/M6 Heteromeric Ion Channels

The transient receptor potential melastatin member 7 (TRPM7) and member 6 (TRPM6) are divalent cation channel kinases essential for magnesium (Mg(2+)) homeostasis in vertebrates. It remains unclear how TRPM6 affects divalent cation transport and whether this involves functional homomeric TRPM6 plasm...

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Autores principales: Zhang, Zheng, Yu, Haijie, Huang, Junhao, Faouzi, Malika, Schmitz, Carsten, Penner, Reinhold, Fleig, Andrea
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931078/
https://ncbi.nlm.nih.gov/pubmed/24385424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.512285
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