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Hydrolysis Rates of Different Small Interfering RNAs (siRNAs) by the RNA Silencing Promoter Complex, C3PO, Determines Their Regulation by Phospholipase Cβ

C3PO plays a key role in promoting RNA-induced gene silencing. C3PO consists of two subunits of the endonuclease translin-associated factor X (TRAX) and six subunits of the nucleotide-binding protein translin. We have found that TRAX binds strongly to phospholipase Cβ (PLCβ), which transmits G prote...

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書目詳細資料
Main Authors: Sahu, Shriya, Philip, Finly, Scarlata, Suzanne
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931071/
https://ncbi.nlm.nih.gov/pubmed/24338081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.531467
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