Selective silencing of DNA topoisomerase IIβ in human mesenchymal stem cells by siRNAs (small interfering RNAs)

hMSCs (human mesenchymal stem cells) express two isoforms of DNA topo II (topoisomerase II). Although both isoforms have the same catalytic activity, they are specialized for different functions in the cell: while topo IIα is essential for chromosome segregation in mitotic cells, topo IIβ is involve...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kamaci, Nebiyyeh, Emnacar, Tuba, Karakas, Nihal, Arikan, Gulsum, Tsutsui, Ken, Isik, Sevim
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Portland Press Ltd 2011
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475440/
https://ncbi.nlm.nih.gov/pubmed/23119146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CBR20110003
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