Selective silencing of DNA topoisomerase IIβ in human mesenchymal stem cells by siRNAs (small interfering RNAs)

hMSCs (human mesenchymal stem cells) express two isoforms of DNA topo II (topoisomerase II). Although both isoforms have the same catalytic activity, they are specialized for different functions in the cell: while topo IIα is essential for chromosome segregation in mitotic cells, topo IIβ is involve...

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Bibliografski detalji
Glavni autori: Kamaci, Nebiyyeh, Emnacar, Tuba, Karakas, Nihal, Arikan, Gulsum, Tsutsui, Ken, Isik, Sevim
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd 2011
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475440/
https://ncbi.nlm.nih.gov/pubmed/23119146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CBR20110003
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