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Crystal Structure of a Bacterial Unsaturated Glucuronyl Hydrolase with Specificity for Heparin
Extracellular matrix molecules such as glycosaminoglycans (GAGs) are typical targets for some pathogenic bacteria, which allow adherence to host cells. Bacterial polysaccharide lyases depolymerize GAGs in β-elimination reactions, and the resulting unsaturated disaccharides are subsequently degraded...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3931040/ https://ncbi.nlm.nih.gov/pubmed/24403065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.522573 |
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