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Crystal Structure of a Bacterial Unsaturated Glucuronyl Hydrolase with Specificity for Heparin

Extracellular matrix molecules such as glycosaminoglycans (GAGs) are typical targets for some pathogenic bacteria, which allow adherence to host cells. Bacterial polysaccharide lyases depolymerize GAGs in β-elimination reactions, and the resulting unsaturated disaccharides are subsequently degraded...

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Detaylı Bibliyografya
Asıl Yazarlar: Nakamichi, Yusuke, Mikami, Bunzo, Murata, Kousaku, Hashimoto, Wataru
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931040/
https://ncbi.nlm.nih.gov/pubmed/24403065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.522573
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