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Crystal Structure of a Bacterial Unsaturated Glucuronyl Hydrolase with Specificity for Heparin

Extracellular matrix molecules such as glycosaminoglycans (GAGs) are typical targets for some pathogenic bacteria, which allow adherence to host cells. Bacterial polysaccharide lyases depolymerize GAGs in β-elimination reactions, and the resulting unsaturated disaccharides are subsequently degraded...

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Hlavní autoři: Nakamichi, Yusuke, Mikami, Bunzo, Murata, Kousaku, Hashimoto, Wataru
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931040/
https://ncbi.nlm.nih.gov/pubmed/24403065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.522573
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