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Thiostrepton-resistant mutants exhibit relaxed synthesis of RNA.

Spontaneous mutants of Bacillus subtilis resistant to thiostrepton (TSP) exhibit relaxed synthesis of RNA when starved for required amino acids. Intact cells of tsp mutants cannot synthesize the regulatory nucleotides, ppGpp and pppGpp, after amino acid deprivation. Because ribosomes isolated from s...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Smith, I, Paress, P, Pestka, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1978
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393103/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/104297/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.12.5993
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