Disrupted Pulmonary Artery Cyclic Guanosine Monophosphate Signaling in Mice with Hyperoxia-Induced Pulmonary Hypertension

Pulmonary hypertension (PH) occurs in 25 to 35% of premature infants with significant bronchopulmonary dysplasia (BPD). Neonatal mice exposed to 14 days of hyperoxia develop BPD-like lung injury and PH. To determinne the impact of hyperoxia on pulmonary artery (PA) cyclic guanosine monophosphate (cG...

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Autors principals: Lee, Keng Jin, Berkelhamer, Sara K., Kim, Gina A., Taylor, Joann M., O’Shea, Kelly M., Steinhorn, Robin H., Farrow, Kathryn N.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2014
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930949/
https://ncbi.nlm.nih.gov/pubmed/24032519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0118OC
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