Bosutinib inhibits migration and invasion via ack1 in kras mutant non-small cell lung cancer

The advent of effective targeted therapeutics has led to increasing emphasis on precise biomarkers for accurate patient stratification. Here, we describe the role of ACK1, a non-receptor tyrosine kinase in abrogating migration and invasion in KRAS mutant lung adenocarcinoma. Bosutinib, which inhibit...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tan, Daniel SW, Haaland, Benjamin, Gan, Jia Min, Tham, Su Chin, Sinha, Indrajit, Tan, Eng Huat, Lim, Kiat Hon, Takano, Angela, Krisna, Sai Sakktee, Thu, Minn Minn Myint, Liew, Hoe Peng, Ullrich, Axel, Lim, Wan-Teck, Chua, Boon Tin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2014
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930897/
https://ncbi.nlm.nih.gov/pubmed/24461128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-13
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