Bosutinib inhibits migration and invasion via ack1 in kras mutant non-small cell lung cancer

The advent of effective targeted therapeutics has led to increasing emphasis on precise biomarkers for accurate patient stratification. Here, we describe the role of ACK1, a non-receptor tyrosine kinase in abrogating migration and invasion in KRAS mutant lung adenocarcinoma. Bosutinib, which inhibit...

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Bibliografiska uppgifter
Huvudupphovsmän: Tan, Daniel SW, Haaland, Benjamin, Gan, Jia Min, Tham, Su Chin, Sinha, Indrajit, Tan, Eng Huat, Lim, Kiat Hon, Takano, Angela, Krisna, Sai Sakktee, Thu, Minn Minn Myint, Liew, Hoe Peng, Ullrich, Axel, Lim, Wan-Teck, Chua, Boon Tin
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2014
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930897/
https://ncbi.nlm.nih.gov/pubmed/24461128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-13
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