Decreased GATA5 mRNA expression associates with CpG island methylation and shortened recurrence-free survival in clear cell renal cell carcinoma

BACKGROUND: GATA-5, a zinc-finger transcription factor and member of the GATA family proteins 1–6, is known to be involved in cellular differentiation. We recently found that tumor-specific hypermethylation of the GATA5 CpG island (CGI) occurs in renal cell carcinoma (RCC) and is associated with an...

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Autors principals: Peters, Inga, Dubrowinskaja, Natalia, Kogosov, Michael, Abbas, Mahmoud, Hennenlotter, Jörg, von Klot, Christoph, Merseburger, Axel S, Stenzl, Arnulf, Scherer, Ralph, Kuczyk, Markus A, Serth, Jürgen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930894/
https://ncbi.nlm.nih.gov/pubmed/24533449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-101
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