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Mutation or Loss of p53 Differentially Modifies TGFβ Action in Ovarian Cancer

Ovarian cancer is the most lethal gynecological disease affecting women in the US. The Cancer Genome Atlas Network identified p53 mutations in 96% of high-grade serous ovarian carcinomas, demonstrating its critical role. Additionally, the Transforming Growth Factor Beta (TGFβ) pathway is dysfunction...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ó hAinmhire, Eoghainín, Quartuccio, Suzanne M., Cheng, Whay, Ahmed, Roshan A., King, Shelby M., Burdette, Joanna E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930740/
https://ncbi.nlm.nih.gov/pubmed/24586866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089553
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