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Increasing Prion Propensity by Hydrophobic Insertion
Prion formation involves the conversion of proteins from a soluble form into an infectious amyloid form. Most yeast prion proteins contain glutamine/asparagine-rich regions that are responsible for prion aggregation. Prion formation by these domains is driven primarily by amino acid composition, not...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3930707/ https://ncbi.nlm.nih.gov/pubmed/24586661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089286 |
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