Topoisomerase Inhibitors Modulate Gene Expression of B-Cell Translocation Gene 2 and Prostate Specific Antigen in Prostate Carcinoma Cells

Camptothecin (CPT) and doxorubicin (DOX) have been demonstrated to have potent anti-tumor activity. The B-cell translocation gene 2 (BTG2) is involved in the regulation of cell cycle progression. We evaluated the molecular mechanisms of CPT and DOX on cell proliferation and the expressions of BTG2 a...

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Autors principals: Chiang, Kun-Chun, Tsui, Ke-Hung, Chung, Li-Chuan, Yeh, Chun-Nan, Chang, Phei-Lang, Chen, Wen-Tsung, Juang, Horng-Heng
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930641/
https://ncbi.nlm.nih.gov/pubmed/24586533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089117
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