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C. elegans CEP-1/p53 and BEC-1 Are Involved in DNA Repair

p53 is a transcription factor that regulates the response to cellular stress. Mammalian p53 functions as a tumor suppressor. The C. elegans p53, cep-1, regulates DNA-damage induced germline cell death by activating the transcription of egl-1 and ced-13. We used the C. elegans model to investigate ho...

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Autori principali: Hoffman, Sandy, Martin, Daniel, Meléndez, Alicia, Bargonetti, Jill
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930633/
https://ncbi.nlm.nih.gov/pubmed/24586407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088828
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