The Chlamydia trachomatis Type III Secretion Chaperone Slc1 Engages Multiple Early Effectors, Including TepP, a Tyrosine-phosphorylated Protein Required for the Recruitment of CrkI-II to Nascent Inclusions and Innate Immune Signaling

Chlamydia trachomatis, the causative agent of trachoma and sexually transmitted infections, employs a type III secretion (T3S) system to deliver effector proteins into host epithelial cells to establish a replicative vacuole. Aside from the phosphoprotein TARP, a Chlamydia effector that promotes act...

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Detalhes bibliográficos
Main Authors: Chen, Yi-Shan, Bastidas, Robert J., Saka, Hector A., Carpenter, Victoria K., Richards, Kristian L., Plano, Gregory V., Valdivia, Raphael H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930595/
https://ncbi.nlm.nih.gov/pubmed/24586162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003954
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