Distinct Requirements for Cranial Ectoderm and Mesenchyme-Derived Wnts in Specification and Differentiation of Osteoblast and Dermal Progenitors

The cranial bones and dermis differentiate from mesenchyme beneath the surface ectoderm. Fate selection in cranial mesenchyme requires the canonical Wnt effector molecule β-catenin, but the relative contribution of Wnt ligand sources in this process remains unknown. Here we show Wnt ligands are expr...

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Main Authors: Goodnough, L. Henry, DiNuoscio, Gregg J., Ferguson, James W., Williams, Trevor, Lang, Richard A., Atit, Radhika P.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930509/
https://ncbi.nlm.nih.gov/pubmed/24586192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004152
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