Distinct Requirements for Cranial Ectoderm and Mesenchyme-Derived Wnts in Specification and Differentiation of Osteoblast and Dermal Progenitors

The cranial bones and dermis differentiate from mesenchyme beneath the surface ectoderm. Fate selection in cranial mesenchyme requires the canonical Wnt effector molecule β-catenin, but the relative contribution of Wnt ligand sources in this process remains unknown. Here we show Wnt ligands are expr...

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Main Authors: Goodnough, L. Henry, DiNuoscio, Gregg J., Ferguson, James W., Williams, Trevor, Lang, Richard A., Atit, Radhika P.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930509/
https://ncbi.nlm.nih.gov/pubmed/24586192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004152
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