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Human monoclonal Fab and human plasma antibodies to carbamyl-epitopes cross-react with malondialdehyde-adducts

Oxidized low-density lipoprotein (OxLDL) plays a crucial role in the development of atherosclerosis. Carbamylated LDL has been suggested to promote atherogenesis in patients with chronic kidney disease. Here we observed that plasma IgG and IgM antibodies to carbamylated epitopes were associated with...

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Detalhes bibliográficos
Main Authors: Kummu, Outi, Turunen, S Pauliina, Prus, Piotr, Lehtimäki, Jaakko, Veneskoski, Marja, Wang, Chunguang, Hörkkö, Sohvi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons Ltd 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930379/
https://ncbi.nlm.nih.gov/pubmed/24168430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12204
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