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Differential Response to Abiraterone Acetate and Di-n-butyl Phthalate in an Androgen-Sensitive Human Fetal Testis Xenograft Bioassay

In utero exposure to antiandrogenic xenobiotics such as di-n-butyl phthalate (DBP) has been linked to congenital defects of the male reproductive tract, including cryptorchidism and hypospadias, as well as later life effects such as testicular cancer and decreased sperm counts. Experimental evidence...

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Autors principals: Spade, Daniel J., Hall, Susan J., Saffarini, Camelia M., Huse, Susan M., McDonnell, Elizabeth V., Boekelheide, Kim
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930360/
https://ncbi.nlm.nih.gov/pubmed/24284787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft266
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