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Differential Response to Abiraterone Acetate and Di-n-butyl Phthalate in an Androgen-Sensitive Human Fetal Testis Xenograft Bioassay

In utero exposure to antiandrogenic xenobiotics such as di-n-butyl phthalate (DBP) has been linked to congenital defects of the male reproductive tract, including cryptorchidism and hypospadias, as well as later life effects such as testicular cancer and decreased sperm counts. Experimental evidence...

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Main Authors: Spade, Daniel J., Hall, Susan J., Saffarini, Camelia M., Huse, Susan M., McDonnell, Elizabeth V., Boekelheide, Kim
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930360/
https://ncbi.nlm.nih.gov/pubmed/24284787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft266
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