Differential Response to Abiraterone Acetate and Di-n-butyl Phthalate in an Androgen-Sensitive Human Fetal Testis Xenograft Bioassay

In utero exposure to antiandrogenic xenobiotics such as di-n-butyl phthalate (DBP) has been linked to congenital defects of the male reproductive tract, including cryptorchidism and hypospadias, as well as later life effects such as testicular cancer and decreased sperm counts. Experimental evidence...

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Main Authors: Spade, Daniel J., Hall, Susan J., Saffarini, Camelia M., Huse, Susan M., McDonnell, Elizabeth V., Boekelheide, Kim
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930360/
https://ncbi.nlm.nih.gov/pubmed/24284787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft266
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