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Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation.

Restriction endonuclease mapping of the human globin genes revealed a genetic variation in a Hpa I recognition site about 5000 nucleotides from the 3' end of the beta-globin structural gene. Instead of a normal 7.6-kilobase (kb) fragment which contains the beta-globin structural gene, 7.0-kb and 13....

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kan, Y W, Dozy, A M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1978
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393021/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/281713/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.11.5631
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