Tumor Angiogenic and Hypoxic Profiles Predict Radiographic Response and Survival in Malignant Astrocytoma Patients Treated With Bevacizumab and Irinotecan

PURPOSE: The combination of a vascular endothelial growth factor (VEGF) -neutralizing antibody, bevaci-zumab, and irinotecan is associated with high radiographic response rates and improved survival outcomes in patients with recurrent malignant gliomas. The aim of these retrospective studies was to...

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Main Authors: Sathornsumetee, Sith, Cao, Yiting, Marcello, Jennifer E., Herndon, James E., McLendon, Roger E., Desjardins, Annick, Friedman, Henry S., Dewhirst, Mark W., Vredenburgh, James J., Rich, Jeremy N.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930173/
https://ncbi.nlm.nih.gov/pubmed/18182667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2007.13.3652
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