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Phase I study of tanespimycin in combination with bortezomib in patients with advanced solid malignancies
PURPOSE: To determine the maximum tolerated dose (MTD) and characterize the dose-limiting toxicities (DLT) of tanespimycin when given in combination with bortezomib. EXPERIMENTAL DESIGN: Phase I dose-escalating trial using a standard cohort “3+3” design performed in patients with advanced solid tumo...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3929968/ https://ncbi.nlm.nih.gov/pubmed/23543109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-013-9946-7 |
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