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Fibroblast Growth Factor-2 Isoform (Low Molecular Weight/18 kDa) Overexpression in Preosteoblast Cells Promotes Bone Regeneration in Critical Size Calvarial Defects in Male Mice

Repair of bone defects remains a significant clinical problem. Bone morphogenetic protein 2 (BMP2) is US Food and Drug Administration–approved for fracture healing but is expensive and has associated morbidity. Studies have shown that targeted overexpression of the 18-kDa low-molecular-weight fibrob...

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Détails bibliographiques
Auteurs principaux: Xiao, Liping, Ueno, Daisuke, Catros, Sylvain, Homer-Bouthiette, Collin, Charles, Lyndon, Kuhn, Liisa, Hurley, Marja M.
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929728/
https://ncbi.nlm.nih.gov/pubmed/24424065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1919
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