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Phosphorylation of Threonine-19 of PSD-95 by GSK-3β is Required for PSD-95 Mobilization and Long-Term Depression

Activity of glycogen synthase kinase-3β (GSK-3β) is required for long-term depression (LTD) via molecular mechanisms that are incompletely understood. Here, we report that PSD-95, a major scaffold protein of the postsynaptic density (PSD) that promotes synaptic strength, is phosphorylated on threoni...

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Detalhes bibliográficos
Main Authors: Nelson, Christopher D., Kim, Myung Jong, Hsin, Honor, Chen, Yelin, Sheng, Morgan
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929687/
https://ncbi.nlm.nih.gov/pubmed/23864697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0131-13.2013
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