Wilms' tumor 1 (Wt1) regulates pleural mesothelial cell plasticity and transition into myofibroblasts in idiopathic pulmonary fibrosis

Pleural mesothelial cells (PMCs), which are derived from the mesoderm, exhibit an extraordinary capacity to undergo phenotypic changes during development and disease. PMC transformation and trafficking has a newly defined role in idiopathic pulmonary fibrosis (IPF); however, the contribution of Wilm...

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Main Authors: Karki, Suman, Surolia, Ranu, Hock, Thomas David, Guroji, Purusotham, Zolak, Jason S., Duggal, Ryan, Ye, Tong, Thannickal, Victor J., Antony, Veena B.
Formato: Artigo
Idioma:Inglês
Publicado: Federation of American Societies for Experimental Biology 2014
Assuntos:
Research Communications
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929684/
https://ncbi.nlm.nih.gov/pubmed/24265486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-236828
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