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Pleural mesothelial cell transformation into myofibroblasts and haptotactic migration in response to TGF-β1 in vitro

Idiopathic pulmonary fibrosis (IPF) is a disease of unknown etiology characterized by the development of subpleural foci of myofibroblasts that contribute to the exuberant fibrosis noted in the pulmonary parenchyma. Pleural mesothelial cells (PMC) are metabolically dynamic cells that cover the lung...

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Autores principales: Nasreen, Najmunnisa, Mohammed, Kamal A., Mubarak, Kamal K., Baz, Maher A., Akindipe, Olufemi A., Fernandez-Bussy, Sebastian, Antony, Veena B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711818/
https://ncbi.nlm.nih.gov/pubmed/19411308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90587.2008
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