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Oxidation of the methionine residues of Escherichia coli ribosomal protein L12 decreases the protein's biological activity.
Oxidation of ribosomal protein L12 with hydrogen peroxide converts the three methionine residues to methionine sulfoxide. The oxidized protein has a decreased ability to bind to ribosomes, interact with ribosomal protein L10, be precipitated by L12 antiserum, and serve as substrate for the acetylati...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1978
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392960/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/364476/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.11.5349 |
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