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Oxidation of the methionine residues of Escherichia coli ribosomal protein L12 decreases the protein's biological activity.

Oxidation of ribosomal protein L12 with hydrogen peroxide converts the three methionine residues to methionine sulfoxide. The oxidized protein has a decreased ability to bind to ribosomes, interact with ribosomal protein L10, be precipitated by L12 antiserum, and serve as substrate for the acetylati...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Caldwell, P, Luk, D C, Weissbach, H, Brot, N
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1978
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392960/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/364476/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.11.5349
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